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USA 111 , 92059210 (2014)

Peptide YY: a potential therapy for obesity

Unlike subcutaneous fat, visceral fat surrounds internal organs and responds poorly to calorie restriction alone

Very interesting paper providing cardiologists point of view on the comparison of semaglutude and tirzepatide They conclude that semaglutide currently remains the most established option for reducing cardiovascular risk in patients with T2DM and obesity with atherosclerotic disease Tirzepatide is particularly well suited when maximal weight reduction represents the primary clinical objective

However, its effect is still controversial, and its mechanism is not clear

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